Associate Professor Dr. Nattaya Ngamrojanavanich

 

Contact Information:

Department of Chemistry, Faculty of Science
Chulalongkorn University
Phayathai Road, Patumwan
Bangkok 10330, THAILAND

 

Office: 1502 Mahamakut Building
Tel: 02-2187635
Fax: 02-2187598
E-mail: nnattaya@chula.ac.th

 

Personal Home Page:  

 

Teaching/Research Field:

Medicinal Chemistry

Natural Product Chemistry

Research Unit(s):

·        Research Centre for Bioorganic Chemistry

 

 

 

Current Research Topics:

·        Organic medicinal Chemistry

·        Natural Product Chemistry

 

Education:

·        1997 Ph.D / Pharmaceutical Science, Tohoku Univrsity,  Japan  

·        1991 M.Sc./ Biotechnology, Chulalongkorn University, Bangkok, Thailand

·        1989 B.Sc./Chemistry, Chiang Mai University, Thailand

 

Work Experiences:

·         

 

Scholarship and Awards:

·        Monbusho Scholarship from the Japanese Government (1992-1996)

 

Publications:

1.       Adisakwattana, S.; Ngamrojanavanich, N.; Kalampakorn, K.; Tiravanit, W.; Roengsumran, S. and Yibchok-Anun, S. "Inhibitory activity of cyanidin-3-rutinoside on alpha-glucosidase." Journal of Enzyme Inhibition and Medicinal Chemistry 2004, 19(4), 313-316.

2.       Adisakwattana, S.; Sookkongwaree, K.; Roengsumran, S.; Petsom, A.; Ngamrojnavanich, N.; Chavasiri, W.; Deesamer, S. and Yibchok-Anun, S. "Structure-activity relationships of trans-cinnamic acid derivatives on alpha-glucosidase inhibition." Bioorganic & Medicinal Chemistry Letters 2004, 14(11), 2893-2896.

3.       Ngamrojnavanich, N.; Sirimongkon, S.; Roengsumran, S.; Petsom, A. and Kamimura, H. "Inhibition of Na+,K+-ATPase activity by (-)-ent-kaur-16-en-19-oic acid and its derivatives." Planta Medica 2003, 69(6), 555-556.

4.       Ngamrojnavanich, N.; Tonsiengsom, S.; Lertpratchya, P.; Roengsumran, S.; Puthong, S. and Petsom, A. "Diterpenoids from the stem barks of Croton robustus." Archives of Pharmacal Research 2003, 26(11), 898-901.

5.       Roengsumran, S.; Ngamrojnavanich, N.; Jaiboon, N.; Tungprapa, S.; Chaichit, N. and Petsom, A. "Crystal structure of 8-chloroandrographolide triacetate." Analytical Sciences 2002, 18(4), 491-492.

6.       Chaichantipyuth, C.; Tiyaworanan, S.; Mekaroonreung, S.; Ngamrojnavanich, N.; Roengsumran, S.; Puthong, S.; Petsom, A. and Ishikawa, T. "Oxidized heptenes from flowers of Melodorum fruticosum." Phytochemistry 2001, 58(8), 1311-1315.

7.       Roengsumran, S.; Petsom, A.; Kuptiyanuwat, N.; Vilaivan, T.; Ngamrojnavanich, N.; Chaichantipyuth, C. and Phuthong, S. "Cytotoxic labdane diterpenoids from Croton oblongifolius." Phytochemistry 2001, 56(1), 103-107.

8.       Roengsumran, S.; Limsuwankesorn, S.; Ngamrojnavanich, N.; Petsom, A.; Chaichantipyuth, C. and Ishikawa, T. "Cassane diterpenoid from Caesalpinia major." Phytochemistry 2000, 53(8), 841-844.

9.       Chairungsrilerd, N.; Furukawa, K.; Ohta, T.; Nozoe, S. and Ohizumi, Y. "gamma-Mangostin, a novel type of 5-hydroxytryptamine 2A receptor antagonist." Naunyn-Schmiedebergs Archives of Pharmacology 1998, 357(1), 25-31.

10.    Chairungsrilerd, N.; Furukawa, K.; Tadano, T.; Kisara, K. and Ohizumi, Y. "Effect of gamma-mangostin through the inhibition of 5-hydroxy-tryptamine(2A) receptors in 5-fluoro-alpha-methyltryptamine-induced head-twitch responses of mice." British Journal of Pharmacology 1998, 123(5), 855-862.

11.    Ohizumi, Y.; Chairungsrilerd, N.; Yoshida, A.; Furukawa, K. and Matsunaga, K. "Phamacological properties of novel serotonin antagonists from natural resources." Naunyn-Schmiedebergs Archives of Pharmacology 1998, 358(1), R107-R107.

12.    Chairungsrilerd, N.; Furukawa, K.I.; Ohta, T.; Nozoe, S. and Ohizumi, Y. "Pharmacological properties of alpha-mangostin, a novel histamine H-1 receptor antagonist." European Journal of Pharmacology 1996, 314(3), 351-356.

13.    Chairungsrilerd, N.; Furukawa, K.I.; Ohta, T.; Nozoe, S. and Ohizumi, Y. "Histaminergic and serotonergic receptor blocking substances from the medicinal plant Garcinia mangostana." Planta Medica 1996, 62(5), 471-472.

14.    Chairungsrilerd, N.; Takeuchi, K.; Ohizumi, Y.; Nozoe, S. and Ohta, T. "Mangostanol, a prenyl xanthone from Garcinia mangostana." Phytochemistry 1996, 43(5), 1099-1102.

15.    Furukawa, K.; Shibusawa, K.; Chairungsrilerd, N.; Ohta, T.; Nozoe, S. and Ohizumi, Y. "The mode of inhibitory action of alpha-mangostin, a novel inhibitor, on the sarcoplasmic reticulum Ca2+-pumping ATPase from rabbit skeletal muscle." Japanese Journal of Pharmacology 1996, 71(4), 337-340.