Assistant Professor Dr. Warinthorn Chavasiri

 

Contact Information:

Department of Chemistry, Faculty of Science
Chulalongkorn University
Phayathai Road, Patumwan
Bangkok 10330, THAILAND

 

Office: 1329 Mahamakut Building
Tel: 02-2187625
Fax: 02-2187598
E-mail: warintho@yahoo.com

 

 

Personal Home Page:  

Teaching/Research Field:

Organic Chemistry

Research Unit(s):

·        Natural Products Research Unit

·        Materials Chemistry and Catalysis Research Unit

Current Research Topics:

·        Methodology in Organic synthesis

·        Chemistry of Natural Products and Agricultural Chemistry

·        Catalysis Applied to Fine chemicals

Education:

·        1993 Ph.D. (Chemistry), Texas A&M University, U.S.A.

·        1988 M.Sc. (Organic Chemistry), Chulalongkorn University, Thailand

·        1985 B.Sc. (Chemistry), Chulalongkorn University, Thailand

Work Experiences:

Academic positions

1993-1995                  Lecturer, Division of Organic Chemistry, Department of Chemistry, Chulalongkorn University, Bangkok, Thailand

1995-present                  Assistant Professor, Division of Organic Chemistry, Department of Chemistry, Chulalongkorn University, Bangkok, Thailand

 

Administrative Positions

1998-2002         Assistant Dean for Research Affairs, Faculty of Science, Chulalongkorn University

2002-2007                     Assistant Dean for Academic Affairs, Faculty of Science, Chulalongkorn University

2007-present      Vice Head of Chemistry Department for Academic Affairs

Scholarship and Awards:

·         

 

Publications:

1.       Kokpol, U.; Chavasiri, W.; Chittawong, V.; Miles, D.H. “Taraxeryl cis-p-Hydroxy cinnamate, A Novel Taraxeryl from Rhizophora apiculataJ. Nat. Prod. 1990, 53, 953-955.

2.       Barton, D.H.R.; Beviere, S.D.; Chavasiri, W.; Csuhai, E.; Doller, D.; Liu, W.-G. “The Functionalization of Saturated Hydrocarbons Part 20 Alkyl Hydroperoxide: Reaction Intermediates in the Oxidation of Saturated Hydrocarbons by Gif-type Reactions and Mechanistic Studies on Their Formation” J. Am. Chem. Soc. 1992, 114, 2147-2156.

3.       Barton, D.H.R.; Beviere, S.D.; Chavasiri, W.; Csuhai, E.; Doller, D “The Functionalization of Saturated Hydrocarbons Part XXI The Fe(III)-Catalyzed and the Cu(II)-Catalyzed Oxidation of Saturated Hydrocarbons by Hydrogen Peroxide: A Comparative Study” Tetrahedron 1992, 48, 2895-2910.

4.       Barton, D.H.R.; Beviere, S.D.; Chavasiri, W.; Doller, D.; Liu, W.-G.; Reibenspies, J.H. “The Functionalization of Saturated Hydrocarbons Part 22 Studies on the Iron Species Responsible for Hydrocarbon Activation by Gif Type Systems” New J. Chem. 1992, 16, 1019-1029.

5.       Barton, D.H.R.; Beviere, S.D.; Chavasiri, W.; Doller, D.; Hu, B. “The Fe(III)-Catalyzed Functionalization of Saturated Hydrocarbons by tert-Butyl Hydroperoxide: Mechanistic Studies on the Role of Dioxygen” Tetrahedron Lett. 1992, 33, 5473-5476.

6.       Barton, D.H.R.; Beviere, S.D.; Chavasiri, W.; Doller, D.; Hu, B. “Metal Dependence in Gif-type Reactions The Cu(II)-catalyzed Olefination of Saturated Hydrocarbons by tert-Butyl Hydroperoxide” Tetrahedron Lett. 1993, 34, 567-570.

7.       Barton, D.H.R.; Beviere, S.D.; Chavasiri, W.; Doller, D.; Hu, B. “New Alkane Functionalization Reactions Based on Gif-type Chemistry in the Presence of Alkali Metal Salts” Tetrahedron Lett. 1993, 34, 1871-1874.

8.       Kokpol, U.; Chavasiri, W.; Chittawong, V.; Bruce, W.; Cunningham, C.N.; Miles, D.H. “Long Chain Aliphatic Alcohols and Saturated Carboxylic Acids from Heartwood of Rhizophora apiculataPhytochemistry 1993, 33, 1129-1131.

9.       Barton, D.H.R.; Chavasiri, W. “The Functionalization of Saturated Hydrocarbons Part 24 The Use of tert-Butyl Hydroperoxide: GoAggIV and GoAggVTetrahedron 1994, 50, 19-30.

10.    Barton, D.H.R.; Chavasiri, W. “The Functionalization of Saturated Hydrocarbons Part 25 Ionic Substitution Reactions in GoAggIV Chemistry: The Formation of Carbon-Halogen Bonds” Tetrahedron 1994, 50, 31-46.

11.    Barton, D.H.R.; Chavasiri, W. “The Functionalization of Saturated Hydrocarbons Part 26 Ionic Substitution Reactions in GoAggIV Chemistry: The Formation of C-N, C-S and C-C Bonds” Tetrahedron 1994, 50, 47-60.

12.    Barton, D.H.R.; Chavasiri, W.; Hill, D.R.; Hu, B. “The Functionalization of Saturated Hydrocarbons Part 27 A New Michael-type Addition Reaction for Saturated Hydrocarbons not Involving Radical Chemsitry” New J. Chem. 1994, 18, 611-620.

13.    Barton, D.H.R.; Beviere, S.D.; Chabot, B.M.; Chavasiri, W.; Taylor, D.K. “Studies on the Oxidation of Alcohols Employing t-Butyl Hydroperoxide (TBHP) and Fe(III)” Tetrahedron Lett. 1994, 35, 4681-4684.

14.    Kokpol, U.; Chavasiri, W.; Tip-pyang, S.; Veerachato, G.; Zhao, F.; Simpson, J.; Weavers, R.T. “A Limonoid from Xylocarpus granatumPhytochemistry 1996, 41, 903-905.

15.    Barton, D.H.R.; Chavasiri, W. “The Functionalization of Saturated Hydrocarbons Part 36 Stereoselectivity Studies of Gif-type Reactions” Tetrahedron 1997, 58, 2997-3004.

16.    Kokpol, U.; Wannachet-isara, N.; Tip-pyang, S.; Chavasiri, W.; Veerachato, G.; Simpson, J.; Weavers, R.T. “A C-Methylflavone from Trianthema portulacastrumPhytochemistry 1997, 44, 719-722.

17.    Chavasiri, W.; Jang, D.O. “The Effects of 1,3-Dicarbonyl Compounds on Alkane Oxidation in Gif-type Reaction” Bull. Korean Chem. Soc. 1997, 18, 362-363.

18.    Chavasiri, W.; Jang, D.O. “Effect of Dicarboxylic Acids on the Rate of Oxidation and Bromination of Cyclododecane under GoAggII Conditions” Bull. Korean Chem. Soc. 2000, 21, 353-354.

19.    Chavasiri, W.; Deesamer, S.; Kokpol, U.; Thipnoisanga, C.; Wattanasereekul, S.; Zungsontiporn, S. “Searching for New Agrochemicals Part 1. Structure Activity Relationship Study of Dicoumarols as Weed Growth Inhibitors against Mimosa pigra Linn.” Thai J. Agric. Science, 2001, 34, 81-89.

20.    Jona, H.; Mandai, H.; Chavasiri, W.; Takeuchi, K.; Mukaiyama, T. “Glycosylation with Glycosyl Fluorides: Protic Acid Catalyzed Stereoselective Glycosylation Using Glycosyl Fluorides” Bull. Chem. Soc. Jpn. 2002, 75, 291-309

21.      Tiew, P.; Puntumchai, A.; Kokpol, U.; Chavasiri, W. “Coumarins from Mansonia gagei Drumm.” Phytochemistry, 2002, 60, 773-776.

22.      Tiew, P.; Ioset, J.-R.; Kokpol, U.; Schenk, K.; Jaiboon, N.; Chaichit, N.; Chavasiri, W.; Hostettmann, K. “Four New Mansonone Derivatives from the Heartwood of Mansonia gageiJ. Nat. Prod. 2002, 65, 1332-1335.

23.      Tiew, P.; Ioset, J.-R.; Kokpol, U.; Chavasiri, W.; Hostettmann, K. “Antifungal, Antioxidant and Larvicidal Activities of Compounds Isolated from the Heartwood of Mansonia gageiPhytother. Res. 2003, 17, 190-193.

24.      Aree, T.; Singhana, B.; Pakawatchai, C.; Chavasiri, W.; Kokpol, U. “10-Hydroxy-9-methoxy-5,6,13,13a-tetrahydro[1,3]dioxolo[4,5g]isoquino[3,2-a]isoquinolin-8-one” Acta Cryst. Sec. E 2003, E59, 919-921.

25.      Tiew, P.; Takayama, H.; Kiyajima, M.; Aimi, N.; Kokpol, U.; Chavasiri, W. “A Novel Neolignan, Mansoxetane, and Two New Sesquiterpenes, Mansonones R and S, from Mansonia gageiTetrahedron Lett. 2003, 44, 6759-6761.

26.    Adisakwattana, S.; Sookkongwaree, K.; Roengsumran, S.; Petsom, A.; Ngamrojnavanich, N. Chavasiri, W.; Deesamer, S.; Yibchok-anun, S. “Structure-Activity Relationships of trans-Cinnamic Acid Derivatives on a-Glucosidase Inhibition” Bioorg. Chem. Lett. 2004, 14, 2893-2896.

27.      Rungprom, W.; Chavasiri, W.; Kokpol, U.; Kotze, A.; Garson, M.J. “Bioactive Chromodorolide Diterpenes from an Aplysillid Sponge” Mar. Drugs, 2004, 3, 101-107.

28.      Munbungjong, W.; Lee, E.H.; Chavasiri, W.; Jang, D.O. “Indium-mediated Mild and Efficient One-pot Synthesis of Alkyl Phenyl SelenidesTetrahedron Lett. 2005, 46, 8769-8771.

29.      Kang, D.H.; Joo, T.Y.; Hwa, E.; Chaysripongkul, S.; Chavasiri, W.; Jang. D.O. “A Mild and Efficient Reaction for Conversion of Carboxylic Acids into Acid Bromides with Ethyl Tribromoacetate/ triphenylphosphine under Acid-free Conditions” Tetrahedron Lett. 2006, 47, 5693-5696.

30.      Morimoto, M.; Ohta, Y.; Ihara, T.; Arima, K.; Fukumoto, H.; Chavasiri, W.; Komai, K.  Insect Antifeedants in the Thailand Plant Extracts against the Common Cutworm, Spodoptera litura, and a Subterranean Termite, Reticulitermes speratus Jpn J Environ Entomol Zool., 2006, 17, 1-7.

31.      Pleumpanupat, W.; Chavasiri, W. “An Efficient Method for Chlorination of Alcohols Using PPh3/Cl3CCONH2Tetrahedron Lett. 2006, 47, 6821-6823.

32.      Morimoto, M.; Fukumoto, H.; Hiratani, M.; Chavasiri, W.; Komai, K. Insect Antifeedants, Pterocarpans and Pterocarpol, In Heartwood of Pterocarpus macrocarpus Kruz.: Biosci. Biotech. Biochem., 2006, 70, 1864-1868.

33.      Chantarasriwong, O.; Jang, D.O.; Chavasiri, W. “A Practical and Efficient Method for the Preparation of Sulfonamides Utilizing Cl3CCN/PPh3Tetrahedron Lett. 2006, 47, 7489-7492.

34.      Intaranongpai, J.; Chavasiri, W.; Gritsanapa, W.Anti-head Lice Component of Annona squamosa SeedSoutheast Asain J. Trop. Med. Public Health, 2006, 37, 532-535.

35.      Pluempanupat, W.; Chantarasriwong, O.; Taboonpong, P.; Jang, D.O.; Chavasiri, W. “Reactivity of Chlorinating Agents for the Chlorination of Alcohols and Carboxylic Acids: A Comparative Study” Tetrahedron Lett. 2007, 48, 223-226.

36.      Kang, D.H.; Joo, T.Y.; Chavasiri, W.; Jang, D.O. “Radical Mediated Direct Conversion of Aldehydes into Acid Bromides” Tetrahedron Lett. 2007, 48, 285-287.

37.      Buranaprasertsuk, P.; Tangsakol, Y.; Chavasiri, W. “Epoxidation of Alkenes Catalyzed by Cobalt(II) Calix[4]pyrrole” Catalytic Commun. 2007, 8,  310-314.

38.      Jarupinthusophon, S.; Thong-in, U.; Chavasiri, W. “Catalytic Oxidative Cleavage of Terminal Olefins by Chromium(III) Stearate” J. Mol. Cat. A, Chem. 2007, 270, 289-294.

39.      Aungsupravate, O.; Kangwansupamonkon, W.; Chavasiri, W.; Kiatkamjornwong, S. “Synthesis and Properties of Solvent Absoptive Methyl Methacrylate-Divinylbenzene Copolymer Beads” Polymer Engineering & Science, 2007, 47, 447-459.

40.      Deesamer, S.; Kokpol, U.; Chavasiri, W.; Douillard, S.; Barbier, P.; Vidal, N.; Combes, S.; Finet, J.-P. “Synthesis and Biological Evaluation of Isoflavone Analogues from Dalbergia oliveri Gamble” Tetrahedron, 2007, 63, 12986-12993.

41.      Pleumpanupat, W.; Adasakwattana, S.; Yibchok-Anun, S.; Chavasiri, W. “Synthesis of N-Phenylphthalimides Derivatives as a-Glucosidase Inhibitor” Arch. Pharm. Res. 2007, 30, 1501-1506. (Impact factor: 0.929) (December)

42.      Tongkate, P., Pluempanupat, W., Chavasiri, W. “Hexabromoacetone and ethyl tribromoacetate: a highly efficient reagent for bromination of alcohol” Tetrahedron Lett., 2008, 49, 1146-1148.

43.      Chang, J.W.W.; Chee, S.; Mak, S.; Buranaprasertsuk, P.; Chan, P.W.H.; Chavasiri, W. Copper-catalyzed Ullmann coupling under ligand and additive free conditions. Part I: O-arylation of phenols with aryl halides Tetrahedron Lett., 2008, 49, 2018-2022.

44.      Buranaprasertsuk, P.; Chang, J.W.W.; Chan, P.W.H.; Chavasiri, W. Copper-catalyzed Ullmann coupling under ligand and additive free conditions. Part II: S-arylation of thiols with aryl iodides Tetrahedron Lett., 2008, 49, 2023-2025.